Stroke Imaging


MRI of acute stroke

MRI is the only imaging technique that can detect stroke injury as early as few minutes after insult. Multi-parameter MRI is increasingly used in the diagnosis of stroke. We have developed multiple MRI techniques including quantitative structural, perfusion, diffusion and functional MRI to image stroke injury with/without treatment.

MRI for monkey brains with stroke
Fig 1. Diffusion weighted images illustrate stroke lesion evolution in an adult rhesus monkey brain.
X Zhang et al, PLOS one, 2015.
Fig 2. Perfusion MRI illustrates temporal perfusion changes in a monkey brain after permanent MCA occlusion. X Zhang et al, PLOS one, 2015
MRI for rat and mouse brains with stroke
Fig 3. Diffusion weighted images (DWI), T2-weighted images (T2WI), ADC maps illustrate stroke lesion evolution in a rat brain with/without treatment.
Wang et al, JNS, 2015.
Fig 4. Diffusion weighted images (DWI), T2-weighted images (T2WI), ADC maps illustrate stroke lesion evolution in a mouse brain with/without treatment.
Wang et al, ISMRM, 2015